英文别名CD4(L3T4); CD4 antigen(p55); CD4 Antigen;CD4 molecule;CD4 Receptor;CD4+Lymphocytedeficiency, included; CD4mut; L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; MGC165891; p55; T CellAntigen T4; T cell antigenT4/LEU3; Tcell differentiation antigen L3T4; T cell OKT4 deficiency,included; T cell surface antigen T4/Leu 3; T cell surface antigen T4/Leu3; T Cell Surface GlycoproteinCD4; W3/25; W3/25 antigen; T-cell surface glycoprotein CD4 isoform 1 precursor; CD4_HUMAN.产品应用WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, Flow-Cyt=1μg/TestNot yet tested in other applications.Optimal working dilutions must be determined by the end user.交叉反应Human, Mouse,Pig (predicted:Rat, Sheep, Cow, Dog, GuineaPig,MACFA)抗体来源Rabbit
Overview Cat. No： DM-11A04-G Format： LiquidHost： Homo Class： MonoclonalType： Antibody Specificity： Binding to RSV F protein Concentration： Please check the label on the tube. Purity ≥95% as determined by SDS-PAGE Purification： Protein A Storage buffer： PBS or Tris-Gly Storage conditions： Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Warning Not for therapeutic use.
Overview Cat. No:DM-A11A04-M Format Liquid Host Homo Class Monoclonal Type Antibody Specificity Binding to RSV F protein Concentration Please check the label on the tube. Purity ≥95% as determined by SDS-PAGE Purification / Storage buffer PBS or Tris-Gly Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Warning Not for therapeutic use.
OverviewCat. No:DM-11A04-G Format: Liquid Host: HomoClass: MonoclonalType: AntibodySpecificity: Binding to RSV F proteinConcentration: Please check the label on the tube. Purity: ≥95% as determined by SDS-PAGE Purification Protein A Storage buffer: PBS or Tris-Gly Storage conditions: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.Warning Not for therapeutic use.
GAPDH Polyclonal Antibody Catalog No DM-Ab-03502Isotype IgG Reactivity Human;Mouse;Rat;Rabbit;Ch;Mk;sheep;X;Fish;Chicken;Guinea pig;Guinea pig;Duck Applications WB;IHC;IF Gene Name GAPDH Protein Name Glyceraldehyde-3-phosphate dehydrogenase Immunogen Recombinant Protein of GAPDH Specificity The antibody detects endogenous GAPDH protein. Formulation PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. Source Polyclonal, Rabbit,IgG Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. Dilution WB: 1:5000 IHC: 1:200. IF 1:50-200 Concentration 1 mg/ml Purity ≥90%Storage Stability -20°C/1 year Synonyms GAPDH; GAPD; CDABP0047; OK/SW-cl.12; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH Observed Band 37kD Cell Pathway Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Membrane . Cytoplasm, cytoskeleton . Translocates to the nucleus following S-nitrosylation Tissue Specificity Astrocytoma,Brain,Cajal-Retzius cell,Colon adenocarcinoma,Epitheliu and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions (PubMed:12829261). .Function catalytic activity:D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = glyceraldehyde-3-phosphate dehydrogenase fami Background glyceraldehyde-3-phosphate dehydrogenase(GAPDH) Homo sapiens Thismatters needing attention Avoid repeated freezing and thawing! Usage suggestions This product can be used in immunological reaction related experiments. For more information, please consult technical personnel. Zhao, Shaorong et al. “Deciphering the performance of polo-like kinase 1 in triple-negative breast cancer progression according to the centromere protein U-phosphorylation pathway.” American journal of cancer research vol. 11,5 2142-2158. 15 May. 2021 3-phospho-D-glyceroyl phosphate + NADH.,function:Independent of its glycolytic activity it is also involved in membrane trafficking in the early secretory pathway.,online information:Glyceraldehyde 3-phosphate dehydrogenase entry,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1.,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.,PTM:Reversible S-nitrosylation of Cys-152 inhibits enzymatic activity and increases endogenous ADP-ribosylation, which inhibits the enzyme in a non-reversible manner. The latter modification is more likely to be a pathophysiological event associated with inhibition of gluconeogenesis.,sequence caution:Differs quite extensively.,similarity:Belongs to the gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferriZhao, TingTing, et al. "Tangshen formula modulates gut Microbiota and reduces gut-derived toxins in diabetic nephropathy rats." Biomedicine & Pharmacotherapy 129 (2020): 110325. Yi, Sheng, et al. "Peripheral nerve injury induces dynamic changes of tight junction components." Frontiers in physiology9 (2018): 1519. Chang, Ying, et al. "Lentivirus-mediated knockdown of astrocyte elevated gene-1 inhibits growth and induces a re p t o in p o to b s la is st t o h m ro a ug c h el M ls.A "P P K loS pa o th n w e a 1 y1 s .2 in (2 h 0 u 1 m 6 a ): n e0148763. Wang, Xiao, et al. "Knockdown of Phospholipase Cɛ (PLCɛ) Inhibits Cell Proliferation via Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)/AKT Signaling Pathway in Human Prostate Cancer." Medical science monitor: international medical journal of experimental and clinical research 24 (2018): 254.
SDHB Polyclonal AntibodyCatalog No dm-04340 Isotype IgG Reactivity Human;Mouse;Rat;Fish Applications WB;IHC;IF;ELISA Gene Name SDHBProtein Name Succinate dehydrogenase [ubiquinone] iron-sulfur subunit mitochondrialImmunogen The antiserum was produced against synthesized peptide derived from the Internal region of human SDHB. AA range:131-180 Specificity SDHB Polyclonal Antibody detects endogenous levels of SDHB protein. Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Source Polyclonal, Rabbit,IgG Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Dilution WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200Concentration 1 mg/ml Purity ≥90% Storage Stability -20°C/1 yearSynonyms SDHB; SDH; SDH1; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur subunit of complex II; IpObserved Band 31kDCell Pathway Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.Tissue Specificity Brain,Fibroblast,Liver, Function catalytic activity:Succinate + ubiquinone = fumarate + ubiquinol.,cofactor:Binds 1 2Fe-2S cluster.,cofactor:Binds 1 3Fe-4S cluster.,cofactor:Binds 1 4Fe-4S cluster.,disease:Defects in SDHB are a cause of Cowden-like syndrome [MIM:612359]. Cowden-like syndrome is a cancer predisposition syndrome associated with elevated risk for tumors of the breast, thyroid, kidney and uterus.,disease:Defects in SDHB are a cause of paraganglioma and gastric stromal sarcoma [MIM:606864]; also called Carney-Stratakis syndrome. Gastrointestinal stromal tumors may be sporadic or inherited in an autosomal dominant manner, alone or as a component of a syndrome associated with other tumors, such as in the context of neurofibromatosis type 1 (NF1). Patients have both gastrointestinal stromal tumors and paragangliomas. Susceptibility to the tumors was inherited in an apparently autosomal dominant m
UQCRFS1 rabbit pAb货号 dm-18000 同位型 IgG 应用 WB 种属 Human;Mouse;Rat 靶点 UQCRFS1 基因名称 UQCRFS1 蛋白名称 Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase ir 免疫原 Synthesized peptide derived from human UQCRFS1特异性 This antibody detects endogenous levels of UQCRFS1 at Human, Mouse,Rat 组成 Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 来源 Polyclonal, Rabbit,IgG 稀释 WB 1:500-2000 纯化工艺 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. 分子量 30kD 功能 [Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation . The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried ac细胞定位 Mitochondrion inner membrane ; Single-pass membrane protein . 浓度 1 mg/ml 储存 -15°C to -25°C/1 year(Do not lower than -25°C) 有关注意事项 Avoid repeated freezing and thawing! 使用建议 This product can be used in immunological reaction related experiments. For more information, please consult technical personnel.
Catalog No dm-16383 Isotype IgG Reactivity Human;Mouse;Rat Applications WB;IHC;IF;ELISA Gene Name ATP5A1 Protein Name ATP synthase subunit alpha mitochondrial Immunogen The antiserum was produced against synthesized peptide derived from human ATP5A1. AA range:201-250 Specificity ATP5A Polyclonal Antibody detects endogenous levels of ATP5A protein. Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Source Polyclonal, Rabbit,IgG Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Dilution WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200Concentration 1 mg/ml Purity ≥90% Storage Stability -20°C/1 yearSynonyms ATP5A1; ATP5A; ATP5AL2; ATPM; ATP synthase subunit alpha; mitochondrial Observed Band 60kD Cell Pathway Mitochondrion . Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side . Cell membrane ; Peripheral membrane protein ; Extracellular side . Colocalizes with HRG on the cell surface of T-cells (PubMed:19285951). . Tissue Specificity Fetal lung, heart, liver, gut and kidney. Expressed at higher levels in the fetal brain, retina and spinal cord. Function function:Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites.,
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